Glimel

What it is used for

Glibenclamide is indicated as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (type 2) whose hyperglycaemia cannot be controlled by diet alone. Because of its broad and predictable action, glibenclamide is often suitable for the management of patients who have failed to respond to other oral antidiabetics.,In initiating treatment for non-insulin-dependent diabetes, diet should be emphasised as the primary form of treatment. Caloric restriction and weight loss are essential in the obese diabetic patient. Proper dietary management alone may be effective in controlling the blood glucose and symptoms of hyperglycaemia. The importance of regular physical activity should also be stressed, and cardiovascular risk factors should be identified and corrective measures taken where possible. If this treatment programme fails to reduce symptoms and/or blood glucose the use of an oral sulfonylurea should be considered. Use of glibenclamide must be viewed by both the physician and patient as a treatment in addition to diet, and not as a substitute for diet or as a convenient mechanism for avoiding dietary restraint.