Ontruzant


What it is used for

Ontruzant is indicated for the treatment of HER2-positive early breast cancer following surgery, and in association with chemotherapy and, if applicable, radiotherapy. Ontruzant is indicated for the treatment of HER2-positive locally advanced breast cancer in combination with neoadjuvant chemotherapy followed by adjuvant Ontruzant. Ontruzant is indicated for the treatment of patients with metastatic breast cancer who have tumours that overexpress HER2: a. as monotherapy for the treatment of those patients who have received one or more chemotherapy regimens for their metastatic disease; b. in combination with taxanes for the treatment of those patients who have not received chemotherapy for their metastatic disease; or c. in combination with an aromatase inhibitor for the treatment of post-menopausal patients with hormone-receptor positive metastatic breast cancer. Ontruzant is indicated in combination with cisplatin and either capecitabine or 5-FU for the treatment of patients with HER2-positive advanced adenocarcinoma of the stomach or gastro-oesophageal junction who have not received prior anti-cancer treatment for their metastatic disease.


How to take it

The way to take this medicine is: Intravenous. This medicine or fluids is given through a needle or tube (catheter) inserted into a vein.

  • Store at 2 to 8 degrees Celsius
  • Refrigerate
  • Do not Freeze
  • Shelf lifetime is 48 Months.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

Always read the label. If symptoms persist see your healthcare professional.


Reporting side effects

You can help ensure medicines are safe by reporting the side effects you experience.

You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems


How to take it

The way to take this medicine is: Intravenous. This medicine or fluids is given through a needle or tube (catheter) inserted into a vein.

  • Store at 2 to 8 degrees Celsius
  • Refrigerate
  • Do not Freeze
  • Shelf lifetime is 48 Months.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

Always read the label. If symptoms persist see your healthcare professional.


Pregnant or planning a pregnancy?

For the active ingredient trastuzumab

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.


Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.


Visual appearance

White to pale yellow, lyophilised powder.

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